Integrating Neurobiological Markers of Depression

Integrating neurobiological markers of depression.

CONTEXT Although psychiatric disorders are, to date, diagnosed on the basis of behavioral symptoms and course of illness, the interest in neurobiological markers of psychiatric disorders has grown substantially in recent years. However, current classification approaches are mainly based on data from a single biomarker, making it difficult to predict disorders characterized by complex patterns o...

Neurobiological markers of familial risk for depression.

Major depression is associated with a wide range of neurobiological disturbances, including anomalies in the structure and function of cortical and subcortical gray matter and dysregulation of the HPA axis. In this chapter, we review research demonstrating that many of these abnormalities are also present in never-depressed offspring of adults with recurrent depression and discuss how such find...

defining bullying: the role of neurobiological markers

Neuropsychotherapy is a relatively young science with strong roots in neurobiology and psychotherapy stretching back to the early twentieth century and the origins of modern neuroscience and psychotherapy. Neuropsychotherapy focuses on therapeutic processes developed specifically to address a range of mental health issues and thereby improve quality of life. Although a strong emphasis is placed...

Towards a neurobiological view of depression

The Neurobiological Impact of Postpartum Maternal Depression

PPD represents a significant public health problemwith prevalence estimates ranging from 12% to 19% and clear negative implications for both maternal and infant health and wellness. Although risk factors for PPD are generally similar to those for depression at other time points in the life course, the substantial neuroendocrine changes that occur in a mother immediately after birth and the sign...